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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR3
All Species:
42.61
Human Site:
S418
Identified Species:
62.5
UniProt:
P61158
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61158
NP_005712.1
418
47371
S418
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001143822
413
46798
R413
L
G
K
Y
C
L
R
R
_
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853309
565
63553
S565
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q99JY9
418
47339
S418
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Rat
Rattus norvegicus
XP_342612
418
47616
S418
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513007
482
55165
S482
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Chicken
Gallus gallus
Q90WD0
418
47403
S418
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Frog
Xenopus laevis
P10995
377
41970
V372
D
E
A
G
P
S
I
V
H
R
K
C
F
_
_
Zebra Danio
Brachydanio rerio
NP_001003944
418
47376
S418
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
O73723
418
47447
S418
N
P
V
F
G
V
M
S
_
_
_
_
_
_
_
Fruit Fly
Dros. melanogaster
P32392
418
47014
T418
N
P
V
F
G
T
M
T
_
_
_
_
_
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4I0
425
48069
T425
N
P
V
F
G
A
L
T
_
_
_
_
_
_
_
Sea Urchin
Strong. purpuratus
XP_780265
418
47124
A418
N
P
V
F
G
A
M
A
_
_
_
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAF1
427
47641
Y427
N
P
V
F
K
G
M
Y
_
_
_
_
_
_
_
Baker's Yeast
Sacchar. cerevisiae
P47117
449
49523
Red Bread Mold
Neurospora crassa
P78712
439
47833
G437
F
A
L
L
G
G
P
G
G
S
_
_
_
_
_
Conservation
Percent
Protein Identity:
100
84.6
N.A.
73.6
N.A.
99.7
91.1
N.A.
78.2
98.5
37.3
97.3
96.6
80.6
N.A.
76
84.6
Protein Similarity:
100
91.8
N.A.
73.8
N.A.
100
96.4
N.A.
83.4
99.7
52.6
99.2
99.5
90.6
N.A.
85.1
92.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
100
0
100
100
75
N.A.
62.5
75
P-Site Similarity:
100
25
N.A.
100
N.A.
100
100
N.A.
100
100
15.3
100
100
87.5
N.A.
87.5
87.5
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.7
59.2
61
Protein Similarity:
N.A.
N.A.
N.A.
74.9
69.2
72.4
P-Site Identity:
N.A.
N.A.
N.A.
62.5
0
10
P-Site Similarity:
N.A.
N.A.
N.A.
62.5
0
30
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
13
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
75
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
7
0
7
75
13
0
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
7
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
7
0
7
7
0
7
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
69
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
75
0
0
7
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
7
0
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
50
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
7
0
13
0
0
0
0
0
0
0
% T
% Val:
0
0
75
0
0
50
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
82
82
88
88
88
94
94
% _